Quest Alliance, a not-for-profit organization dedicated to building 21st-century skills and empowering young learners, has received a significant trust-based grant from philanthropist MacKenzie Scott. The unrestricted grant provides Quest Alliance with the flexibility to invest in organization development and education technology, focusing on increasing impact and addressing urgent disruptions such as climate change and technological advancements. This grant enables Quest Alliance to drive deeper systemic change in the school-to-work ecosystem, transform the learning experience, and equip youth with the skills needed for the future.